Auer rods in mature granulocytes and monocytes.

Auer rods in mature granulocytes of a patient with mixed lineage leukemia.

A 17-year-old previously healthy male presented with an incidental finding of pancytopenia and circulating blast cells in the peripheral blood. Bone marrow aspirate and biopsy showed a large population of blast cells. Blast cells showed variability in size, variable amount of cytoplasm, and vacuoles in the cytoplasm. Some contained azurophilic granules. The nuclei were irregular with folding an...

Auer rods in unusual sites: macrophage indigestion

Mature neutrophils with Auer rods following treatment with all-trans retinoic acid for acute promyelocytic leukemia.

A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 3 10 /mL) with 13% atypical promyelocytes, anemia (hemoglobin of 6.8 g/dL), and thrombocytopenia (41 000 per mL). The atypical promyelocytes were medium to large in size with frequent bilobed nuclei, fine chromatin, and abundant cytoplasmic granules with occasional Auer rods. She was diagnosed with acute...

Auer Rods Are Not Seen in Non-Neoplastic Cells

First I would like to thank Smeeta Gajendra for scrutinizing my article in her ‘Comment: In Response to “Auer Rod-Like Inclusions in Reactive Plasma Cells in a Case of Acute Myeloid Leukemia”’ published online and for bringing to light the missing reference of Sharma et al. [1], who reported a case of Auer rodlike inclusions in plasma cells in a case of therapy-related AML. I sincerely regret m...

Crystal structure of Auer rods in acute myeloblastic leukaemia (AMyL).

Ultrathin sections containing Auer rods from cases of acute myeloblastic leukaemia (AMyL) were tilted in the goniometer stage of the electron microscope and the resulting series of electronmicrographs analysed in an optical diffractometer illuminated by laser. The results showed that Auer rods of AMyL show a truly three dimensional crystal structure. Measurements from the optical diffraction pa...